An Israeli historian Dina Porat claimed that the Final Solution, i.e.: "the systematic overall physical extermination of Jewish communities one after the other – began in Lithuania" during the massive German chase after the Red Army across the Baltic states in Reichskommissariat Ostland.[53] The subject of the Holocaust in Lithuania has been analysed by Konrad Kweit from USHMM who wrote: "Lithuanian Jews were among the first victims of the Holocaust [beyond the eastern borders of occupied Poland]. The Germans carried out the mass executions [...] signaling the beginning of the 'Final Solution'."[54] About 80,000 Jews were killed in Lithuania by October (including in formerly Polish Wilno) and about 175,000 by the end of 1941 according to official reports.[53]
In his monograph, The Origins Of The Final Solution: The Evolution of Nazi Jewish Policy, September 1939 – March 1942, Christopher Browning argues that Nazi policy toward the Jews was radicalized twice: in September 1939, when the invasion of Poland implied policies of mass expulsion and massive loss of Jewish lives; and in spring 1941, when preparation for Operation Barbarossa involved the planning of mass execution, mass expulsion, and starvation – to dwarf what had happened in Jewish Poland.[113]
Nevertheless, some acts of rescue seem to have been unplanned, spontaneous extensions of a general habit to help the needy. Indeed, most rescuers do not appear to have thought carefully about their actions or analyzed them; instead, they viewed their assistance to Jews as a natural reaction to human suffering. Some even insisted in postwar interviews that there was nothing special about what they did to save Jewish lives. Only a small fraction of rescuers saw their saving of Jews as extraordinary. A large majority of rescuers described aiding Jews because they were in pain and in need, while just over one-quarter said that they helped because it was a Christian duty. About half saw their actions as a protest against the occupation. For some rescuers, such attitudes required protecting even people they disliked.

Half a year later, Harel was replaced by Meir Amit, who ordered the Mossad to “stop chasing after ghosts from the past and devote all our manpower and resources to threats against the security of the state.” He mandated that the agency deal with Nazis “only to the extent it is able to do so, in addition to its principal missions” and as long as “it doesn’t impinge on the other operations.”
One day this past fall I walked the grounds of the Ponar forest with Freund­ and a couple of his colleagues, who had recently completed a surveying project of the area. Snow had been forecast, but by late morning the only precipitation was icy rain, driven sideways by the wind. The forest was mostly empty, save for a group of ten Israelis who had arrived that morning; they all had family from Vilnius, one of the men explained, and were honoring them by visiting local Holocaust sites.
After obtaining a copy of his birth certificate through the West German embassy in 1956, Mengele was issued with an Argentine foreign residence permit under his real name. He used this document to obtain a West German passport, also using his real name, and embarked on a trip to Europe.[71][72] He met up with his son Rolf (who was told Mengele was his "Uncle Fritz")[73] and his widowed sister-in-law Martha, for a ski holiday in Switzerland; he also spent a week in his home town of Günzburg.[74][75] When he returned to Argentina in September 1956, Mengele began living under his real name. Martha and her son Karl Heinz followed about a month later, and the three began living together. Josef and Martha were married in 1958 while on holiday in Uruguay, and they bought a house in Buenos Aires.[71][76] Mengele's business interests now included part ownership of Fadro Farm, a pharmaceutical company.[74] Along with several other doctors, Mengele was questioned in 1958 on suspicion of practicing medicine without a license when a teenage girl died after an abortion, but he was released without charge. Aware that the publicity would lead to his Nazi background and wartime activities being discovered, he took an extended business trip to Paraguay and was granted citizenship there in 1959 under the name "José Mengele".[77] He returned to Buenos Aires several times to settle his business affairs and visit his family. Martha and Karl lived in a boarding house in the city until December 1960, when they returned to Germany.[78]
The Germans invaded the Netherlands, Luxembourg, Belgium, and France in May 1940. In the Netherlands, the Germans installed Arthur Seyss-Inquart as Reichskommissar, who quickly began to persecute the approximately 140,000 Dutch Jews. Jews were forced out of their jobs and had to register with the government. Non-Jewish Dutch citizens protested these measures, and in February 1941 they staged a strike that was quickly crushed.[161] After Belgium's surrender at the end of May 1940, it was ruled by a German military governor, Alexander von Falkenhausen, who enacted anti-Jewish measures against the country's 90,000 Jews, many of whom were refugees from Germany or Eastern Europe.[162]
In the first phase of the experiments, pairs of twins and persons with inherited anomalies were put at the disposal of Dr. Mengele and subjected to all imaginable specialist medical examinations. They were also photographed, plaster casts were made of their jaws and teeth, and they were toe- and fingerprinted. As soon as these examinations were finished, they were killed with lethal injections of phenol to the heart so that the next phase of the experimentation could begin: autopsies and the comparative analysis of their internal organs.
At the same time, a carefully orchestrated smear campaign under the direction of Propaganda Minister Joseph Goebbels portrayed Jews as enemies of the German people. Daily anti-Semitic slurs appeared in Nazi newspapers, on posters, the movies, radio, in speeches by Hitler and top Nazis, and in the classroom. As a result, State-sanctioned anti-Semitism became the norm throughout Germany. The Jews lost everything, including their homes and businesses, with no protest or public outcry from non-Jewish Germans. The devastating Nazi propaganda film The Eternal Jew went so far as to compared Jews to plague carrying rats, a foreshadow of things to come.

Mengele sailed to Argentina in July 1949, assisted by a network of former SS members. He initially lived in and around Buenos Aires, then fled to Paraguay in 1959 and Brazil in 1960, while being sought by West Germany, Israel, and Nazi hunters such as Simon Wiesenthal who wanted to bring him to trial. He eluded capture in spite of extradition requests by the West German government and clandestine operations by the Israeli intelligence agency Mossad. He drowned in 1979 after suffering a stroke while swimming off the Brazilian coast, and was buried under a false name. His remains were disinterred and positively identified by forensic examination in 1985.