From 1933 until 1938, most of the people held in concentration camps were political prisoners and people the Nazis labeled as "asocial." These included the disabled, the homeless, and the mentally ill. After Kristallnacht in 1938, the persecution of Jews became more organized. This led to the exponential increase in the number of Jews sent to concentration camps.
While there were only 23 main camps between 1933 to 1945, the Nazi regime established some 20,000 other camps used for forced labor, transit or temporary internment. During the Holocaust it is estimated that 6 million Jews were slaughtered along with, 3 million Soviet prisoners of war, 3 million Polish Catholics, 700,000 Serbians, 250,000 Gypsies, Sinti, and Lalleri, 80,000 Germans (for political reasons), 70,000 German handicapped, 12,000 homosexuals, and 2,500 Jehovah’s Witnesses.
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At the Wannsee Conference on January 20, 1942 in Wannsee, a Berlin suburb, the details of the “Final Solution” were worked out. The meeting was convened by Reinhard Heydrich, who was the head of the S.S. main office and S.S. Chief Heinrich Himmler’s top aide. The purpose of the meeting was to coordinate the Nazi bureaucracy required to carry out the “Final Solution,” which provided for:
Yet any projection of Anne Frank as a contemporary figure is an unholy speculation: it tampers with history, with reality, with deadly truth. “When I write,” she confided, “I can shake off all my cares. My sorrow disappears, my spirits are revived!” But she could not shake off her capture and annihilation, and there are no diary entries to register and memorialize the snuffing of her spirit. Anne Frank was discovered, seized, and deported; she and her mother and sister and millions of others were extinguished in a program calculated to assure the cruellest and most demonically inventive human degradation. The atrocities she endured were ruthlessly and purposefully devised, from indexing by tattoo through systematic starvation to factory-efficient murder. She was designated to be erased from the living, to leave no grave, no sign, no physical trace of any kind. Her fault—her crime—was having been born a Jew, and as such she was classified among those who had no right to exist: not as a subject people, not as an inferior breed, not even as usable slaves. The military and civilian apparatus of an entire society was organized to obliterate her as a contaminant, in the way of a noxious and repellent insect. Zyklon B, the lethal fumigant poured into the gas chambers, was, pointedly, a roach poison.