Because of this book, we will remember the names, the quirks -- the characters -- of the eight people who inhabited the secret annex and their brave Dutch helpers. We will be able to visualize them long after everyone who witnessed that horrific era is gone. It is because of Anne's diary that she and her family are among the few we will remember -- the ones we feel we know -- among the millions who suffered and died as she did.

After invading Poland, the Germans established ghettos in the incorporated territories and General Government to confine Jews.[143] The ghettos were formed and closed off from the outside world at different times and for different reasons.[196][197] For example, the Łódź ghetto was closed in April 1940,[143] to force the Jews inside to give up money and valuables;[198] the Warsaw ghetto was closed for health considerations (for the people outside, not inside, the ghetto),[199] but this did not happen until November 1940;[143] and the Kraków ghetto was not established until March 1941.[200] The Warsaw Ghetto contained 380,000 people[143] and was the largest ghetto in Poland; the Łódź Ghetto was the second largest,[201] holding between 160,000[202] to 223,000.[203] Because of the long drawn-out process of establishing ghettos, it is unlikely that they were originally considered part of a systematic attempt to eliminate Jews completely.[204]
Within one week from the start of Operation Barbarossa, Heydrich issued an order to his Einsatzkommandos for the on-the-spot execution of all Bolsheviks, interpreted by the SS to mean all Jews. One of the first indiscriminate massacres of men, women, and children in Reichskommissariat Ukraine took the lives of over 4,000 Polish Jews in occupied Łuck on 2–4 July 1941, murdered by Einsatzkommando 4a assisted by the Ukrainian People's Militia.[55] Formed officially on 20 August 1941, the Reichskommissariat Ukraine – stretching from prewar east-central Poland to Crimea – had become operational theatre of the Einsatzgruppe C. Within the Soviet Union proper, between 9 July 1941 and 19 September 1941 the city of Zhytomyr was made Judenfrei in three murder operations conducted by German and Ukrainian police in which 10,000 Jews perished.[41] In the Kamianets-Podilskyi massacre of 26–28 August 1941 some 23,600 Jews were shot in front of open pits (including 14,000–18,000 people expelled from Hungary).[41][56] After an incident in Bila Tserkva in which 90 small children left behind had to be shot separately, Blobel requested that Jewish mothers hold them in their arms during mass shootings.[57][58] Long before the conference at Wannsee, 28,000 Jews were shot by SS and Ukrainian military in Vinnytsia on 22 September 1941, followed by the 29 September massacre of 33,771 Jews at Babi Yar.[41][59] In Dnipropetrovsk, on 13 October 1941 some 10,000–15,000 Jews were shot.[60] In Chernihiv, 10,000 Jews were put to death and only 260 Jews were spared.[60] In mid-October, during the Krivoy-Rog massacre of 4,000–5,000 Soviet Jews the entire Ukrainian auxiliary police force actively participated.[61] In the first days of January 1942 in Kharkiv, 12,000 Jews were murdered, but smaller massacres continued in this period on daily basis in countless other locations.[60] In August 1942 in the presence of only a few German SS men over 5,000 Jews were massacred in Polish Zofjówka by the Ukrainian Auxiliary Police leading to the town's complete sweep from existence.[62]
In the decades that followed the Nuremburg Trials, in which Nazi officials, charged with crimes against peace and humanity, hid behind the excuse that they were just following orders, historians grappled with questions of blame and guilt. Had Hitler and top Nazi officials been solely responsible for the genocide? How complicit were lower-level Nazis and members of the Order Police?
At Auschwitz, a large new camp was already under construction to be known as Auschwitz II (Birkenau). This would become the future site of four large gas chambers to be used for mass extermination. The idea of using gas chambers originated during the Euthanasia Program, the so-called "mercy killing" of sick and disabled persons in Germany and Austria by Nazi doctors.
In 1935, Mengele earned a PhD in anthropology from the University of Munich.[7] In January 1937, he joined the Institute for Hereditary Biology and Racial Hygiene in Frankfurt, where he worked for Dr. Otmar Freiherr von Verschuer, a German geneticist with a particular interest in researching twins.[7] As von Verschuer's assistant, Mengele focused on the genetic factors that result in a cleft lip and palate, or a cleft chin.[10] His thesis on the subject earned him a cum laude doctorate in medicine (MD) from the University of Frankfurt in 1938.[11] (Both of his degrees were revoked by the issuing universities in the 1960s.)[12] In a letter of recommendation, von Verschuer praised Mengele's reliability and his ability to verbally present complex material in a clear manner.[13] The American author Robert Jay Lifton notes that Mengele's published works were in keeping with the scientific mainstream of the time, and would probably have been viewed as valid scientific efforts even outside Nazi Germany.[13]