Throughout the Middle Ages in Europe, Jews were subjected to antisemitism based on Christian theology, which blamed them for killing Jesus. Even after the Reformation, Catholicism and Lutheranism continued to persecute Jews, accusing them of blood libels and subjecting them to pogroms and expulsions. The second half of the 19th century saw the emergence in the German empire and Austria-Hungary of the völkisch movement, which was developed by such thinkers as Houston Stewart Chamberlain and Paul de Lagarde. The movement embraced a pseudo-scientific racism that viewed Jews as a race whose members were locked in mortal combat with the Aryan race for world domination. These ideas became commonplace throughout Germany, with the professional classes adopting an ideology that did not see humans as racial equals with equal hereditary value. Although the völkisch parties had support in elections at first, by 1914 they were no longer influential. This did not mean that antisemitism had disappeared; instead it was incorporated into the platforms of several mainstream political parties.
On January 20, 1942, Reinhard Heydrich, head of the Reich Security Head Office, convened all secretaries of state of the major German ministries to the Wannsee Conference. This conference is generally held to have been a major turning point, whereby the “final solution of the Jewish question” in Europe by “evacuation” to the East and by other “means” was decided upon. But in fact, the mass extermination of the Jews on an industrial scale, made possible by the creation of death camps, was launched prior to this notorious conference.
Mengele sailed to Argentina in July 1949, assisted by a network of former SS members. He initially lived in and around Buenos Aires, then fled to Paraguay in 1959 and Brazil in 1960, while being sought by West Germany, Israel, and Nazi hunters such as Simon Wiesenthal who wanted to bring him to trial. He eluded capture in spite of extradition requests by the West German government and clandestine operations by the Israeli intelligence agency Mossad. He drowned in 1979 after suffering a stroke while swimming off the Brazilian coast, and was buried under a false name. His remains were disinterred and positively identified by forensic examination in 1985.