The Generalplan Ost ("General Plan for the East") called for deporting the population of occupied Eastern Europe and the Soviet Union to Siberia, for use as slave labour or to be murdered.[321] To determine who should be killed, Himmler created the Volksliste, a system of classification of people deemed to be of German blood.[322] He ordered that those of Germanic descent who refused to be classified as ethnic Germans should be deported to concentration camps, have their children taken away, or be assigned to forced labour.[323][324] The plan also included the kidnapping of children deemed to have Aryan-Nordic traits, who were presumed to be of German descent.[325] The goal was to implement Generalplan Ost after the conquest of the Soviet Union, but when the invasion failed Hitler had to consider other options.[321][326] One suggestion was a mass forced deportation of Jews to Poland, Palestine, or Madagascar.[317]
Umbreit, Hans (2003). "Hitler's Europe: The German Sphere of Power". In Kroener, Bernhard; Müller, Rolf-Dieter; Umbreit, Hans. Germany and the Second World War, Vol. 5. Organization and Mobilization in the German Sphere of Power. Part 2: Wartime Administration, Economy, and Manpower Resources, 1942–1944/5. Oxford; New York: Oxford University Press. ISBN 978-0-19-820873-0.

Victor Kugler, Johannes Kleiman, Miep Gies, and Bep Voskuijl were the only employees who knew of the people in hiding. Along with Gies' husband Jan Gies and Voskuijl's father Johannes Hendrik Voskuijl, they were the "helpers" for the duration of their confinement. The only connection between the outside world and the occupants of the house, they kept the occupants informed of war news and political developments. They catered to all of their needs, ensured their safety, and supplied them with food, a task that grew more difficult with the passage of time. Frank wrote of their dedication and of their efforts to boost morale within the household during the most dangerous of times. All were aware that, if caught, they could face the death penalty for sheltering Jews.[25]

When Hitler became chancellor of Germany on January 1, 1933, conditions for Jews like the Franks and other so-called undesirables in Germany immediately deteriorated. By summer, freedom of speech and assembly were suspended for everyone in Germany, the Gestapo was formed, Jewish businesses—including medical and legal practices—were boycotted, and a law excluding non-Aryans from government removed Jews from government and teaching positions.
Nazi Germany maintained concentration camps (German: Konzentrationslager, KZ or KL) throughout the territories it controlled before and during the Second World War. The first Nazi camps were erected in Germany in March 1933 immediately after Hitler became Chancellor and his Nazi Party was given control of the police by Reich Interior Minister Wilhelm Frick and Prussian Acting Interior Minister Hermann Göring.[2] Used to hold and torture political opponents and union organizers, the camps initially held around 45,000 prisoners.[3] In 1933–1939, before the onset of war, most prisoners consisted of German Communists, Socialists, Social Democrats, Roma, Jehovah's Witnesses, homosexuals, and persons accused of 'asocial' or socially 'deviant' behavior by the Germans.[4]