As long as Rosé remained in charge of the orchestra, it maintained a fairly high level of skill and a large repertoire. The musicians participated in strenuous rehearsals and even more stressful concerts and private performances. Although the vast majority of their music-making was (with the exception of the daily march music) for the benefit of the SS and the small group of ‘elite’ prisoners, the orchestra would occasionally give special concerts to the regular inmates, and make visits to the infirmary. However, upon Rosé's sudden and mysterious death on 4 April 1944, the orchestra began to slowly crumble. Rosé was replaced by the Ukrainian pianist and copyist Sonya Winogradowa, who, although liked by the other musicians, was not a particularly effective leader. At the end of 1944, the non-Jewish members were sent to Auschwitz I, while the Jews were deported to Bergen-Belsen. Relatively many survived the war.
Some ghettos were initially open, which meant that Jews could leave the area during the daytime but had to be back by a curfew. Later, all ghettos became closed, meaning that Jews were not allowed to leave under any circumstances. Major ghettos were located in the cities of Polish cities of Bialystok, Lodz, and Warsaw. Other ghettos were found in present-day Minsk, Belarus; Riga, Latvia; and Vilna, Lithuania. The largest ghetto was in Warsaw. At its peak in March 1941, some 445,000 were crammed into an area just 1.3 square miles in size.
The Luftwaffe did end up with an air force consisting mainly of relatively short-range aircraft, but this does not prove that the German air force was solely interested in ’tactical’ bombing. It happened because the German aircraft industry lacked the experience to build a long-range bomber fleet quickly, and because Hitler was insistent on the very rapid creation of a numerically large force. It is also significant that Germany's position in the centre of Europe to a large extent obviated the need to make a clear distinction between bombers suitable only for ’tactical’ and those necessary for strategic purposes in the early stages of a likely future war.
Meanwhile, beginning in the fall of 1939, Nazi officials selected around 70,000 Germans institutionalized for mental illness or disabilities to be gassed to death in the so-called Euthanasia Program. After prominent German religious leaders protested, Hitler put an end to the program in August 1941, though killings of the disabled continued in secrecy, and by 1945 some 275,000 people deemed handicapped from all over Europe had been killed. In hindsight, it seems clear that the Euthanasia Program functioned as a pilot for the Holocaust.
The United States Holocaust Memorial Museum defines the Holocaust as the "systematic, bureaucratic, state-sponsored persecution and murder of six million Jews by the Nazi regime and its collaborators", distinguishing between the Holocaust and the targeting of other groups during "the era of the Holocaust". According to Yad Vashem, Israel's Holocaust memorial, most historians regard the start of the "Holocaust era" as January 1933, when Hitler was named Chancellor of Germany. Other victims of the Holocaust era include those viewed as inferior, including for reasons of race or ethnicity (such as the Roma, ethnic Poles, Russians, and the disabled); and those targeted because of their beliefs or behavior (such as Jehovah's Witnesses, communists, and homosexuals). Hitler came to see the Jews as "uniquely dangerous to Germany", according to Peter Hayes, "and therefore uniquely destined to disappear completely from the Reich and all territories subordinate to it". The persecution and murder of other groups was much less consistent. For example, he writes, the Nazis regarded the Slavs as "sub-human", but their treatment consisted of "enslavement and gradual attrition", while "some Slavs—Slovaks, Croats, Bulgarians, some Ukrainians—[were] allotted a favored place in Hitler's New Order".
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The first mass transport to Auschwitz I, which included Catholic prisoners, suspected members of the Polish resistance, and 20 Jews, arrived on 14 June 1940 from prison in Tarnów, Poland. They were interned in the former building of the Polish Tobacco Monopoly, adjacent to the site, until the camp was ready. By the end of 1940, the SS had confiscated land around the camp to create a 40-square-kilometre (15 sq mi) "zone of interest" surrounded by a double ring of electrified barbed wire fences and watchtowers. The inmate population grew quickly as the camp absorbed Poland's intelligentsia and dissidents. By March 1941, 10,900 were imprisoned there, most of them Poles.
From 1942, members of the Bureau of Information and Propaganda of the Warsaw-area Home Army published reports based on the accounts of escapees. The first was a fictional memoir, "Oświęcim. Pamiętnik więźnia" ("Auschwitz: Diary of a prisoner") by Halina Krahelska, published in April 1942 in Warsaw. Also published in 1942 was the pamphlet Obóz śmierci (Camp of Death) by Natalia Zarembina, and W piekle (In Hell) by Zofia Kossak-Szczucka, founder of Żegota. In March 1944, the Polish Labor Group in New York published a report in English, "Oswiecim, Camp of Death (Underground Report)", with a foreword by Florence Jaffray Harriman, which described the gassing of prisoners from 1942.
In September 1939, the German army occupied the western half of Poland. German police soon forced tens of thousands of Polish Jews from their homes and into ghettoes, giving their confiscated properties to ethnic Germans (non-Jews outside Germany who identified as German), Germans from the Reich or Polish gentiles. Surrounded by high walls and barbed wire, the Jewish ghettoes in Poland functioned like captive city-states, governed by Jewish Councils. In addition to widespread unemployment, poverty and hunger, overpopulation made the ghettoes breeding grounds for disease such as typhus.